Treatment-Resistant Depression

Ketamine Assisted Therapy with Injections for Treatment-Resistant Depression in Johns Creek

Treatment-resistant depression care in Johns Creek

Treatment-Resistant Depression

If you suffer from depression, you can rely on Stephanie Nnamchi, NP, and the expert mental health team at Vigor Health Services based in Johns Creek, Georgia. While depression can affect your quality of life, it doesn’t have to.

At Vigor Wellness Space, we offer Ketamine-Assisted Therapy using intramuscular injections as one of the most effective options available for individuals with treatment-resistant depression, especially those who have not found adequate relief from traditional antidepressants, therapy, or other standard treatments.

Ketamine-Assisted Therapy may offer a new path forward when depression has been stubborn, long-lasting, or unresponsive to traditional treatment.
Schedule a Consultation

How Ketamine-Assisted Therapy Helps Treat Treatment-Resistant Depression

Ketamine works through a completely different mechanism than conventional antidepressants. Instead of targeting serotonin or norepinephrine, it rapidly enhances neuroplasticity while helping reset overactive stress pathways.

1

Rapid Antidepressant Effects

Many individuals notice significant mood improvement within hours to a few days after the first session, far faster than traditional medications.

2

Reduction in Symptoms

Patients may experience decreases in persistent sadness, hopelessness, fatigue, and loss of interest or pleasure in life.

3

Relief from Suicidal Ideation

Ketamine has shown strong, rapid effects in reducing suicidal thoughts in many patients who need faster support.

4

Improved Motivation

Patients often report feeling more present, more emotionally connected, and better able to engage in daily life and relationships.

5

Longer-Lasting Results

A series of treatments, followed by proper integration, can help create sustained improvements for many people.

A New Path Forward

Ketamine may help create a window for healing when traditional treatments have not provided enough relief.

Why Intramuscular Injections?

At Vigor Wellness Space, IM ketamine injections are used because they allow for a smooth, comfortable, and carefully monitored experience.

  • Precise, personalized dosing based on your individual response
  • A smooth and comfortable experience without the need for IV lines
  • An ideal therapeutic window that supports emotional processing
  • Excellent safety with continuous monitoring by a board-certified psychiatric provider

What the Research Shows

Ketamine is one of the most well-studied and effective treatments for treatment-resistant depression. Multiple clinical trials and real-world studies have demonstrated rapid and clinically significant improvement in 60–70% of patients who did not respond to other treatments. For many, a short series of sessions can help break the cycle of chronic depression and create a window for lasting recovery.

Is Ketamine-Assisted Therapy Right for You?

Ketamine-Assisted Therapy may be especially beneficial if depression has continued despite your best efforts with other forms of care.

  • You have tried multiple antidepressants or therapies with little or no success
  • You struggle with severe, persistent depression that affects daily functioning
  • You experience depression with or without anxiety, trauma, or suicidal thoughts
  • You are looking for a fast-acting treatment that addresses neurological patterns of depression
A typical protocol includes a series of IM sessions over 2–3 weeks, followed by maintenance treatments as needed to sustain benefits. All sessions take place in a calm, supportive environment with full medical supervision and therapeutic guidance.
Request An Appointment

Treatment Contraindications

Our services strive to help improve mental and physical well-being. Therefore, certain conditions may be contraindicated for your health.

Where indicated, medical clearance from your doctor may be warranted for safety. Conditions such as heart failure, end-stage kidney disease, cancer, and pregnancy may require additional review.

Treatment Combinations

Several treatment therapies may be necessary to achieve optimum results and outcomes.

Outcome Timeline

We ask that you give each treatment at least 12 weeks or more for full effectiveness when compliant with your personalized treatment plan.